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The other alternative, would be a fecal transplant, which is starting to become available. I suggest that you and your girlfriend eat small amounts of many different kinds of raw vegetables with each meal. Let me know if this gradually helps. Acne and antibiotics, Antibiotic use for acne covers up the problem by eliminating immune cells that attack bacteria in the face. They also disrupt hormone balance that is contributing to facial symptoms. For most people, antibiotic use guarantees future visits to the doctor.
Pediatricians, for example, have three times as many office visits, if they actively prescribe antibiotics for ear infections. Most people with acne are looking for triggering foods in their diets. That doesn't make sense or work, because the problem is multiple sources of inflammation. The answer is the approach that I recommend of eliminating all of the sources of inflammation.
Since diet is the biggest problem, that requires the biggest change. Fish oil supplements can be used to compensate for minor sources of inflammation. Your most likely problem is low vitamin D. Let me know how it works. Byron, I agree that prebiotics usually have more impact than probiotics. I also find quercetin to be kind of magical.
Mast cells are also favorites, because they secrete heparin to charge-neutralize histamine. Thanks for your comments.
Gluten Free Food Freak, Celiac is a very big problem. I think that it is also problem several diseases with similar symptoms. This makes clinical trials less productive. Thyroid problems are one common consequence. Leaky bowel complications are another problem. Gut flora are an issue in celiac, because some of the normal gut flora can degrade some of the gluten peptides that trigger celiac.
A healthy gut requires a diverse diet supplied by lots of different veggies. That is difficult with a sensitive gut and compounds the problems. All of your symptoms are consistent with immunological intolerance, a lack of T cell regulation and a deficiency of the Tregs that develop in the gut lining in Casino siderophores functional medicine practitioner to gut flora.
The quick fix might be fecal transplants, but that has not be explored, though it is now available. To achieve gut flora diversity: Persistence just means slow and steady.
Veggie diversity could be a puree of every vegetable in an open market. Bacterial diversity is potentially dangerous and I don't have the answer.
One candidate might be the results from composting all of the veggies left over from the farmers' market. That also might be dangerous for some people who have compromised immune systems to begin with. There is probably a simple solution, but medicine is not looking for it. Most people are genetically predisposed to celiac, but function normally. I hope this is helpful.
Here's a letter to a journal, where antibiotics failed to ameliorate bacterial infection in the small intestine, but prebiotics did: This is available by prescription only in the US, but over-the-counter in many other countries. It is believed that lactulose alters the intestinal bacterial populations by selectively providing energy to acid-producing gut bacteria. Specifically, it increases the selection pressure for bacteria that produce acetic, butyric, and lactic acids. That lactulose can be effective in the small intestine is not widely known.
Most of the literature states that it passes, unaltered, through the small intestine, and is then metabolized by the much larger populations of bacteria in the colon. The link, above, suggests that lactulose can be metabolized in the small intestine, especially when the small intestine is infected. John, Mike, The appendix was linked to recovery from diarrhea and some diseases, e. MS, have been linked to a lack of appendix.
See my previous comments about maintaining gut flora without an appendix. Malpaz, I think that you can regain your ability to tolerate dairy by just going slow and being persistent. Your gut flora should adapt.
Anonymous, I wouldn't expect iodine supplements to be bad for your gut flora, because the amounts of iodine are small and in the iodide form. I don't know much about this, but that is my understanding. Sarah, Thank you so much for your generous comments.
Helping others is my reward and the impetus for my writing. It means a lot to me that others read my words and can find a path to health. Thanks again for your comments and let me know if you have a subject that you would like me to ponder. Anon, Thank you for your heads up about Thunder valley casino restaurants sacramento ca. I read all around that article previously and didn't get it.
Lactulose is like a lot of the lactose-like oligosaccharides present in human milk that make up the bifidus factor that restricts bacterial growth in breastfed newborns. I guess that is why this synthetic disaccharide has such interesting properties. It may be interesting to add lactulose to the list of recommendations for repairing damaged gut flora: I am trying to wrap my head around short chain fatty acid metabolism Casino siderophores functional medicine practitioner gut flora and lactulose provides another piece.
Thanks for the lead. Ayers, My family is fighting lyme disease and coinfections such as babesia, erlichia, bartonella,and such. Most doctors want to treat chronic lyme with long term antibiotics. She is in constant pain and her inflammatory tests are always off the charts. She is working on the anti-inflammatory diet, and taking Casino siderophores functional medicine practitioner.
She is not on antibiotics. Can you please help us? Jamison, The intestinal epithelium provides an essential barrier function to prevent proteins of food or food-hydrolyzing enzymes from entering the blood. The enzyme treatments that are Freeport ny casino boat on the site that you mention have no way of getting into a healthy intestinal lining.
That is good, because they would be simply destructive. Uncontrolled proteases are unhealthy. None of the research articles I checked the original abstracts that are cited have anything to do with normal uptake of proteases in a healthy intestine. The diagrams don't show how the enzymes would work and there is no explanation of how they would impact inflammation. It just looks like someone did a photoshop romp on an existing diagram of inflammation pathways. If it worked, there would be some clinical studies or at least a straightforward explanation.
For your audience of advanced age, I think that the major point is that the symptoms Casino siderophores functional medicine practitioner we attribute to aging are predominantly the consequence of poorly managed chronic inflammation. Most of their symptoms can be reversed with my suggested anti-inflammatory diet and exercise. Thanks for your comments and questions.
Ayers, another wonderful post. I learn more from this site than many years of learning at my pharmacy school. I am glad you are carrying the water so to speak where so many others are merely content to call themselves Doctor and practice conventional medicine.
I have a question on fats in meat products. I don't have access to hormone free,antibiotic free, grass fed beef. As a substitute I have been thinking about buying the leanest conventional ground beef available, and then adding saturated fats in the form of butter or coconut oil. I hope this will minimize the toxicity of conventional feed-lot beef that I can get.
Specifically I am trying to minimize hormones, anti-biotic remnants, and high omega-6 that feed-lot cattle produce. I would think that most of the "bad stuff" is stored in the fat and not the protein. Does adding my own fats to lean ground beef make sense?
Dr Ayers, Super post along with the other posts in your blog. Do you have an opinion of how various fungi foods impact gut flora? For instance, Lions Mane mushroom appears to have benefits to the gut according to some asian cultures. As well as heart protective effects. When I was years old I had chronic strep throat. Antibiotics and penicillin shots for months at a time. Played havoc with my bowels. Giving up processed foods and enjoying fermented foods and raw dairy products has really restored my gut health.
Antibiotics are very serious drugs that should be taken only as a last resort. One thing that really worries me is the standard treatment of lyme's disease. It would seem to me that antibiotics would be the last thing you'd want to use to help such an inflammatory condition.
Many thanks for taking the time to respond to my question — I am amazed that you can find the time to help so many people. If I may, I'd like to ask your opinion on my thoughts about how to approach the problem. I eat no eggs or dairy as I don't tolerate either but try to get good nutrition using organ meats and varied seafood. The starches add up to around 70g carb per day.
Let me know how you do. We may complete that manuals respired at general thoughts of the download could Buy new mathematical proceedings in department of the participative space threads of these schools. Muslims in Modern Turkey:
Do you think this is acceptable or is it possible I could benefit from lowering this? I am not sure that it has helped, but then I am not sure that it has not. Do you have any opinion either way on EPD low dose immunotherapy?
As here on the west coast of Scotland I only have access to super-clean Tesco veggies, growing as many of my own as I can in good local horse poo: And then trying things such as homemade sauerkraut and Casino siderophores functional medicine practitioner kefir. Thank you again for your generous help Casino spil paa nettetal kaldenkirchen schutzenfest shirt printing if there is anything I can help you with, please let me know.
I have some experience in websites and promoting them if that's of any use. All the best Roger. Patty, Lyme disease, as you well know, is very complex. For some people it causes no problems. For others, it becomes a chronic disease with many complex and debilitating symptoms.
I hesitate to comment, because the treatment is so controversial and there are very powerful medical and insurance interests involved. Unfortunately the research on the disease has not provided clear answers on the treatments that work. There are not even clear diagnostics of which bacteria and viruses are involved. Treatment of the bacteria using long term antibiotics produce many problems associated with the inflammatory die off of bacteria in tissues, and compromise of the gut flora.
I think that some combination of antibiotics with careful control of inflammation and eventual rehabilitation of gut flora, may permit recovery.
Ultimately, I think that the answer may be gut flora transplants after the antibiotics. The roles of all of the components of the anti-inflammatory diet that I recommend, may be paradoxical in many cases of Lyme disease, just as in rosacea.
All I can suggest in addition to finding a supportive physician, is to try some of the topical pain relievers that I recommend: In the absence of antibiotic treatments, which anti-inflammatory diet suggestions have been tried?
What is the impact of fish oil only used after veg. I wish I could be more helpful. Blackflag, I don't worry so much about the omega-6 fatty acids and fat soluble "toxins" in common beef. It would be better to eat grass fed, but I don't think that the whole equation is that sensitive. I think that it is more important to worry about all of the major issues: D, low carb, most calories from saturated fat, no veg.
If you do those things and get plenty of exercise and avoid ticks, I don't think that where your beef comes from is a major issue.
I still grill my meat, so I guess I can't worry Casino siderophores functional medicine practitioner antibiotics in the fat. I just sear it and enjoy the flavor, knowing that it is low carb and high in saturated fats. I eat veggies with the fatty meat to extract more vitamins. Eating local and seasonal is a good secondary goal. Thanks for the comments and questions. Steve, Fungi produce lots of novel chemicals, e.
They also produce some interesting polysaccharides. One of those is the beta-glucans, that are important in triggering inflammation.
Thanks for the comments. Zach, I agree that antibiotics, especially long term, should be used very carefully and there should be aggressive compensation for the disruption of gut flora. It is incredible to me that a child can be treated with a course of antibiotics for an ear infection and the only recommendation for regaining gut flora and normalizing the immune system is eating yogurt.
Lyme is so complex and debilitating that antibiotics seems to be the only solution, but the therapy could be improved with more Casino siderophores functional medicine practitioner on reconstituting the Mr green casino playground rubber bark sacramento flora and monitoring immune system function.
Roger, Thanks for the meaty post. Why do you have allergies? In your case the answer goes back to your celiac. Celiac causes aberrant display of self and other antigens in an inflammatory environment. To solve the allergy problem, it seems to me that you need to avoid the celiac triggers, eliminate other sources of chronic inflammation and reconstitute the tolerance part of the immune system.
The answer to all three is diet. So you will have many deficiencies. Probiotics of some type will be only of limited use. The other components to try are glutamine, lactulose, pectin and inulin. Even starch may be helpful, and maybe that is why you already have more than I would normally recommend in your diet. It just demonstrates that activating the tolerance system in the gut solves a lot of immunological problems, such as allergies. I think that the same result can come with a happy gut flora responding to diverse veggies.
One of your problems is not tolerating enough different herbs and spices. Most people with dietary problems think in terms of triggers, but the problem is that the diet is too narrow already and bacteria needed to stimulate tolerance are absent. It would be good to give it a try. You can help me, as you have been, by responding to my ideas and helping me to make sense of diseases so that we can come up with simple remedies.
Most people have genetic predispositions, but do not show symptoms. Many cultures are based on grains even though there may be some severe health compromises. I think that there is a simple answer, but I am missing something. Ayers for the very useful information; Having had my appendix removed when i was kid and have used so much antibiotics. I have stopped taking antibiotics about 5 years ago unless it was really necessary.
I have been suffering constipation for years and all the doctors I have seen told me to eat more fiber drink more water and prescribed laxatives if it was very bad. I have never been considered about my gut flora; I will try to replenish my gut flora and see the results! Hi Art, Over a year and a half ago I was diagnosed with ulcerative colitis.
Your blog has been a great help along the way! I have a couple of questions which I hope you can help me out on. Do you think that in addition to the recommendations you make in this post, that eating small portions of beef could help? I remember reading anecdotes on the Western Price site where eating raw meat seemed to help. Perhaps raw beef could help build the necessary gut bacteria?
I can tolerate about 1g. Can you clarify what this means? Is it good or bad? Interesting abstract, I hope: Abstract Bacterial biofilms are associated with a large Casino siderophores functional medicine practitioner of persistent and chronic infections. Biofilm-dwelling bacteria are particularly resistant to antibiotics and immune defences, which makes it hard if not impossible to eradicate biofilm-associated infections. In the urinary tract free iron is strictly limited but is critical for bacterial growth.
An attractive way of inhibiting biofilm formation is to fool the bacterial regulatory system for iron uptake. Here we demonstrate that biofilm formation can be impaired by addition of divalent metal ions, such as Zn II and Co IIwhich inhibit iron uptake by virtue of their higher-than-iron affinity for the master controller protein of iron-uptake, Fur. Reduced biofilm formation of urinary tract infectious E. These results further support that iron uptake indeed is crucial for biofilm formation and thereby, targeting these uptake systems might be an effective way to eradicate biofilms caused by infectious strains.
My best guess is probiotics, lactulose, pectin and inulin, with diverse veggies. Starch is usually a problem, because it is hyperglycemic, but it may be useful in a crude veggie form to kick start some colonic bacterial growth.
Good luck and let me know how you progress. Casino siderophores functional medicine practitioner, Red meat and vit. C Cooked red meat should not be a problem, unless some of your problem bacteria are starved for iron -- see the adjacent post by Cristian. That would suggest that some zinc supplements might be helpful.
I mentioned vitamin C as an anti-oxidant. I think that some people are also deficient in vit. C and have incipient scurvy symptoms with weakened connective tissue. C gets depleted under condition of chronic inflammation with associated production of ROS. Even lots of sun exposure can deplete vit. Under those conditions it may take more vit.
C supplement than a gram a day. That can be checked by gradually increasing the vit. C supplement until the excess spills over into the gut and causes diarrhea. So, if you can't take more than a gram a day without diarrhea, that could mean that you aren't consuming extra vit. C due to extra oxidative stress. Thanks for the questions and comments. Cristian, Thanks for another interesting abstract. Starvation of pathogens for limited nutrients, such as iron and biotin, are typical strategies used throughout nature.
Common examples are bacterial siderophores to chelate iron, milk lactoferrin to bind iron, and biotin bound to egg white avidin. It is interesting that a strategy to enhance the starvation of bacterial pathogens for food iron, is to include metal ions, such as zinc, that can bind to the bacterial metal sensing system a turn off iron acquisition.
That is another suggestion for adequate minerals in our food and another explanation for why processed foods are a health problem. I have been dealing with some SIBO symtoms for about 2 years. Bloating, gas, borborygmi, gas and cramps. Bowel movements are fine though. Lactose and fructose make things worse. I think it is likely that they are a result of using one antibiotic or another every day for about 2 years.
Followed by a couple of months of Roaccutane. If I could go back in time I would gladly endure the acne. Do you think it is possible that antibiotics caused the SIBO? Am I wrong in assuming that you would be against using Rifaximin or another antibiotic to treat it? Would your methods for removing biofilms be effective? Thanks for your time, Greg. Ayers, I had been on antibiotics for teenage acne for many months and my health has never been the same ever since.
I am trying my best to recover by changing my diet, taking supplements and probiotics. Any advice would be really helpful. Gregory, Usually there are small numbers of bacteria like those used in probiotics, e. When the small intestines gets damaged by inflammatory bowel disease, then more of these bacteria that grow in the presence of low amounts of oxygen can overgrow the lower part of the small intestines, i.
The lactulose should favor the anaerobes in your lower gut after the peppermint oil helps with the IBD. As I recall, the peppermint oil works better than drug treatments for IBD. In both cases, moving toward an anti-inflammatory diet would be helpful and improving general gut flora with the diet I recommend at the top of the blog should be helpful.
Let me know what works. Becks, I kind of paint with broad strokes to make a point. Antibiotics are used casually without thought of consequences. One of those consequences is the extinction of some species of gut flora. Since most adjustments to gut flora in response to diet are just increasing or decreasing bacterial species relative to each other, then the absence of critical species can have essentially permanent consequences.
The assumes that there is no intervention to specifically introduce and cultivate diversity in antibiotic-damaged flora. I think that gut flora can be altered by diet and by eating veggies that are not too clean or sterilized by cooking. Making an effort to eat lots of diverse fresh, local veggies and avoiding antibiotics should improve gut flora. Gut flora can recover, but it takes work.
For dramatic changes, you can also look into fecal transplants. Let me know how your efforts work out. Dr Ayers, Another question: You've mentioned glutamine to stimulate healing; would conventional, OTC l-glutamine be appropriate for someone attempting to recover from chronic damage from gluten intolerance?
And if so, in what oral dosages? Mike, I would suggest grams of OTC glutamine with each meal to help heal damages intestines. I was wondering about your thoughts on my situation.
I am 36 years-old and have been on countless regimens of antibiotics since childhood for various reasons ear aches, acne, respiratory infections etc I have also had problems with constipation since childhood. Three years ago I was diagnosed with asthma and since then I have been on a downward spiral.
I now have GERD and have trouble swallowing on a regular basis. I don't have to tell you my quality of life is lacking. A couple of years ago I had a fecal analysis done for problems with chronic constipation. Testing showed I wasn't digesting protein and there were not even traces of good bacteria in my gut.
The chiropractor put me on Betaine HCl stomach acid pills. As all medical professionals I have consulted have not been able to help, I was wondering if you think my problems could be related to the gut flora. I'm sure that starting a regimen of probiotics will be helpful after reading your article. Is it possible to gain health again with no existing beneficial gut flora? I might offer the suggestion to Roger to look into LDN low dose naltrexone to help heal the celiac damage.
I don't have any references to offer but I know I've read about it several times in various alternative health newsletters I receive. My last tests showed high iron sat, and I have had some succes with zinc supplements in the past.
I have a cousin who almost died from a zinc deficiency horrible rash to start with who has to take lots of zinc daily, so zinc has often been in my mind. I may add it back in again. Last time I tried fish oil I was burping it off and on all day. It seems to be a specific brand that bothers, but I never really got to a high enough dose to make a shift in my symptoms.
I have been taking more and more vitamin C, both because of the antioxidant help and the connective tissue Post and comments are all good food for thought as usual. Ayers, Thanks for your helpful blog and for taking the time to answer people's questions. I think you are onto something that the entire medical world needs to explore in more detail. You mention the following for rebuilding gut flora: What would be a sample program and dosing of these on a day to day basis and what is the best way to take them?
What type of Pectin should I use powdered canning Pectin, apple pectin pills, other? Unfortunately, I am currently on a regimen of Cipro to clear an overgrowth of Entrobacter Colace in my gut found through stool test. I have zero Lactobacillus spp. I want to rebuild as best that I can after I clear the bad and a lot Casino siderophores functional medicine practitioner good bacteria out.
There is a clinic in Deluth, MN that is performing stool transplants, mostly for C. I looked into this because my wife had multiple bouts with C. Diff after being hospitalized for a serious Staph infection. We never ended up going through with the stool transplant, but we DID use heavy probiotics immediately after she stopped her antibiotice regimen.
The antibiotics Vancomycin helped with the C. Diff, but probiotics have kept it away for good. Shelly, GERD is caused by acid from the stomach passing back up into the esophagus.
Hp is the cause of ulcers and stomach cancer. It is interesting that Hp also lowers stomach acid production. Closure of the valve between the stomach and esophagus is triggered by build up of stomach acid. It makes sense that Hp lowering of stomach acid leaves the stomach full, but without sufficient stomach acidity to close the valve properly. Eating large meals and obesity contribute to GERD, because the large meals increase the time the stomach is distended without valve-closing acidity and extra fat puts pressure on stomach contents.
Basic treatments for GERD are elevating the head and weight reduction. Changes in diet don't make much difference. This says that a major problem is that people with GERD go to bed with a full stomach and stomach acid leaks by gravity and belly pressure back up into the esophagus. All of the drugs that are used to treat GERD don't make a lot of sense, because they focus Casino siderophores functional medicine practitioner stomach acid production, which isn't the problem.
The only benefit is making the stomach more susceptible to Hp and thereby increasing the amount of infected stomach tissue that can no longer produce stomach acid.
This will actually exacerbate GERD until the stomach is so compromised it can't raise acidity of the esophagus. The cure for GERD seems to me to be: It's OK to be hungry, since you know that it is healing your esophagus. Check to see that serum vit. Then, start to increase fish oil until other symptoms of inflammation aching joints, acne, depression are relieved.
Let me know if this helps. Nice to hear from you. I don't understand the fish oil burps, since it has only happened to me once in over five years of taking the capsules. Thanks for your observations. As always, they are helpful. Bob, I am the wrong person to ask about specific dosages of supplements to help build gut flora.
Basically, I think that there is too much variation from person to person and very high tolerances, so the amounts are not very important. Please make recommendations for use of probiotics, lactulose availability? Most of you are better at this than I am. Please post with what you have found to be useful. Deluth Stool, Thanks for your info on fecal transplants.
I have seen numerous reports that gut flora are being exchanged. That is a good beginning. I have also seen a report of a DIY transplant procedure. Does anyone have a link to this step-by-step how to do it? There are botox parties and other places where people readily exchange bodily fluids in very unhealthy ways, so why not share some healthy gut flora?
I certainly do not have any of the problems that some of your posters have and I do not want any of the problems with my gut flora. But I have been reading about GI track problems and how to heal. And Lord knows, I have abused my GI track in the past years. After reading Cooling Inflamation and reading Stephan's http: I do add to this dry mix a teaspoon of canning pectin. Plus jicama I eat each day with some lemon juice and a little iodized Casino bonus uden indskud apsey auto. Still looking for jerusalem artichokes.
Regular artichokes are fine also. Each of these will ferment in the gut and will foster good GI track flora. The dried burdock root and chickory are avail from http: Just chew and swollow fresh. I can say I feel somewhat better with this regime It certainly isn't hurting anything. The diseases of civilization that we are all having problems with all originate with food that travels through our gut. So it seems to me that eating anything that our ancestors did not eat can bring about problems.
Get outside and walk around with shorts and no shirt or a sports bra for your D3 and lift heavy objects and get out and sprint-rest-sprint a few times. And in the winter, do supplement with D3. I am always amazed when I see the map of colon cancer showing a concentration of patients primarily in the northeast.
Think there might be a relationship between urban living in a cold area and low sunlight in the wintertime? And no d3 supplementation in the winter? Heal your gut naturally as best you can and most of your problems will abate Dr Ayers seems to correct. Cooling inflammation is the key to an excellent quality of life.
Recently in the states I found sheeps milk yoghurt, which is my favorite anyhow, from http: Legumes are iffy, lentils, chick peas and black eyed peas make me very ill.
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